Ivabradine effectively prevents heart rate increase, however, has no effect on cardiac arrhythmias during dobutamine infusion: a comparative study with beta-blocker therapy
نویسندگان
چکیده
منابع مشابه
Heart failure: ivabradine is no better than optimised beta-blocker therapy.
In a double-blind randomised placebo-controlled trial including about 6500 heart failure patients, ivabradine did not reduce overall mortality or cardiovascular mortality. Ivabradine reduced mortality due to heart failure, but not in the subgroup of patients receiving at least half the recommended dose of a beta-blocker. In a double-blind randomised placebo-controlled trial in about 10 000 pati...
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RESULTS OF INVESTIGATIONS performed on animals indicate that halothane anaesthesia increases the sensitivity of the myocardial tissues to epinephrine. 1-s In man, ventricular arrhythmias may follow the use of the epinephrine. ~'7 This investigation was undertaken to study the usefulness of an adrenergic/3-receptor blocking agent (Pronethalol)f in preventing and/or correcting cardiac arrhythmias...
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BACKGROUND The results of randomised control trials (RCTs) evaluating the effect of beta-blockers on functional status in patients with chronic heart failure are conflicting. AIM To perform a systematic review and meta-analysis of RCTs evaluating the effect of beta-blockers on New York Heart Association (NYHA) classification and exercise tolerance in chronic heart failure. METHODS AND RESUL...
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Perioperative myocardial infarction is a major cause of complications and death among patients undergoing noncardiac surgery. 1 Annually in the United States, approximately 27 million patients are given anesthesia for surgical procedures; of these, approximately 50,000 patients have a perioperative myocardial infarction. 2 The pathophysiology of an acute perioperative myocardial infarction is p...
متن کاملCardiac chronotropic responsiveness to beta-adrenoceptor stimulation is not reduced in the elderly.
OBJECTIVES This study evaluated cardiac beta-adrenoceptor responsiveness in the elderly. BACKGROUND The hypothesis of reduced cardiac beta-adrenoceptor responsiveness in the elderly is based on a smaller increase in heart rate after administration of isoproterenol, a nonselective beta 1- and beta 2-adrenoceptor agonist. By means of dobutamine-stress-echocardiography we were able to retest the...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2013
ISSN: 0195-668X,1522-9645
DOI: 10.1093/eurheartj/eht309.p3307